A large pile of human skulls and bones is depicted in this painting, creating a dark and macabre scene. The skulls are stacked on top of each other, some partially obscured by bones. The painting is done in a realistic style, with a focus on detail. The artist has captured the texture of the bone and the darkness of the skulls, creating a sense of eeriness. The painting evokes a sense of death and decay, and may be a representation of the fragility of life.